Antimalarial Activity of Extract and Fractions of Sauropus androgynus (L.) Merr.

Table 4

Percentages of inhibition of parasite growth in mice infected with P. berghei treated orally by doses of ethanolic leaf extract of S. androgynus for 8 consecutive days before and after infection (D₀−D₇).

Treatments	Dose (mg/kg/day)	% Parasitaemia		% Inhibition
		Day 6	Day 10
Na CMC	—	0.26 ± 0.26	11.65 ± 1.50	—
Ethanolic leaf extract of S. androgynus	100	1.00 ± 0.14	5.51 ± 0.13	52.70 ± 1.93
	200	0.92 ± 0.15	4.04 ± 0.54	65.30 ± 10.44
Doxycycline	13	0.00 ± 0.00	3.47 ± 0.36	70.23 ± 6.88

Data are expressed as mean ± SEM; n = 5; significance relative to the negative control, .