Sleep Disorders

Research Article

Characteristics of Obese Patients with Acute Hypercapnia Respiratory Failure Admitted in the Department of Pneumology: An Observational Study of a North African Population

Table 2

Laboratory data of patients at admission.


	Specimens , %	Total sample ()	Nm-OHS ()	M-OHS ()

Glucose serum level, mmol/l (median, IQR)	43 (97.7)	6.9 (2.7–27.9)	6.9 (2.7–24)	6.8 (4.7–27.9)	0.65
BUN, mmol/l (median, IQR)	43 (97.7)	8.4 (2.7–35)	8.7 (2.7–19.6)	8.4 (4.2–35)	0.89
Serum creatinine level, μmol/l (median, IQR)	44 (100)	89.5 (42.7–281)	85 (42.7–183)	93 (47–281)	0.24
Creatinine clearance, ml/min (mean, SD)	44 (100)	67.1 (29.4)	69.9 (27.9)	61.6 (32.5)	0.38
AST, U/l (median, IQR)	42 (95.5)	15.5 (2–67)	16.5 (2–44)	14 (8–67)	0.94
ALT, U/l (median, IQR)	42 (95.5)	16 (6–49)	16 (6–49)	17 (6–42)	0.63
HB, g/dl (median, IQR)	44 (100)	12.9 (6.6–21.2)	13.4 (6.6–21.2)	12.5 (10.7–16.1)	0.52
Hematocrit, %	44 (100)	41.5 (30.7–65)	42.7 (7.3)	41.6 (4.4)	0.57
PLQ, e/ml (mean, SD)	44 (100)	228.84 (60.157)	226.48 (66.180)	233.40 (48.186)	0.72
WBC, e/ml (mean, SD)	44 (100)	8.911 (2.502)	8.596 (2.762)	9.520 (1.837)	0.25
Troponin, μg/L (median, IQR)	36 (81.8)	0.03 (0–64)	0.02 (0–0.54)	0.04 (0.0–64)	0.4
Pro-BNP, pg/mL (median, IQR)	30 (68.2)	267 (18–7414)	135 (18–2524)	500 (30.3–7414)	0.2
CRP, mg/L (median, IQR)	40 (90.9)	9.5 (2–356)	9 (2–62)	16.9 (5–356)	0.48
TSH, mUI/L (median, IQR)	23 (52.3)	2.1 (0.25–9.95)	1.82 (0.45–5.66)	2.11 (0.25–9.95)	0.78
Serum protein, g/l (mean, SD)	22 (50)	72.7 (6.2)	74.3 (6.3)	70.3 (5.6)	0.15
pH (median, IQR)	44 (100)	7.33 (7.20–7.35)	7.33 (7.20–7.35)	7.33 (7.27–7.35)	0.5
PaCO2, mmHg (median, IQR)	44 (100)	59.6 (46–97.2)	59 (48.5–97.2)	61 (46–86.3)	0.59
PaO2, mmHg (median, IQR)	44 (100)	60 (34–149)	60 (34–90)	61 (40–149)	0.98
HCO₃^-, mmol/l (mean, SD)	44 (100)	32 (5.1)	31.8 (5)	32.2 (5.4)	0.83
SaO₂, % (median, IQR)	44 (100)	87.1 (55.7–99)	86.3 (55.7–99)	87.9 (67–99)	0.79

Nm-OHS: nonmalignant obesity hypoventilation syndrome; M-OHS: malignant OHS; : value; IQR: interquartile range; SD: standard deviation; BUN: blood urea nitrogen; AST: aspartate aminotransferase; ALT: alanine aminotransferases; HB: hemoglobin; PLQ: platelet count; WBC: white blood cells; Pro-BNP: probrain natriuretic peptide; CRP: C-reactive protein; TSH: thyroid-stimulating hormone. : mean (standard deviation). : median (interquartile range). PaCO₂: arterial partial pressure of carbon dioxide; PaO₂: arterial partial pressure of oxygen; HCO3-: concentration of bicarbonate in arterial blood; SaO₂: oxyhemoglobin saturation of arterial blood gas.