Research Article

Duodenal Perforation: Outcomes after Surgical Management at a Tertiary Care Centre—A Retrospective Cross-Sectional Study

Table 1

Demographic data, preoperative, intraoperative, and postoperative variables, and outcomes of duodenal perforation. Association of aetiological factors with outcome variables.

NAetiology variables
Ulcer (%)ERCP (%)Postsurgery (%)Trauma (%) value

Total Patients5525 (46 %)15 (27%)11 (20%)4 (7.3%)
Age (years)
 Mean52.356.85151.1330.185
 Range16–8125–7529–8123–6916–48
 Male38 (69.1%)18 (72)6 (40)10 (90)4 (100)0.016
 Female17 (30.9%)7 (28)9 (60)1 (10)0

Indication for ERCPCholedocholithiasis11 (73%)
Benign biliary stricture3 (20%)
Malignancy1 (7%)

Inadvertent injury during surgeryLaparoscopic cholecystectomy4 (36%)
Right hemicolectomy2 (18%)
Pancreatic necrosectomy2 (18%)
Right nephrectomy2 (18%)
Enterocutaneous (jejunal) fistula1 (9.1%)

Duration to surgery (days)
 Mean4.623.84.46.55.20.156
 Range0–201–120–200–201–13

Preoperative organ failure
 Yes23 (41.8)11 (44)7 (46)2 (18)2 (50)0.320
 No32 (58.2)14 (56)8 (54)9 (82)2 (50)

BOEY score
0 (3.6%)1 (4%)1 (6.6%)00
1 (38%)7 (28%)7 (47%)5 (46%)2 (50%)
2 (42%)12 (48%)5 (33%)4 (36%)2 (50%)
3 (5.4%)5 (20%)2 (13.3%)1 (9%)0

Surgery
 Repair18 (33%)
 Repair + diversion28 (51%)
 Diversion6 (11%)
 Resection3 (5.4%)

Location
 D127 (49)23 (92)02 (18)2 (50)
 D228 (51)2 (8)15 (100)9 (82)2 (50)

Hospital stay (days)
 Mean17
 Range0–70

ICU stay (days)0.049
 Mean5.9
 Range0–28

Leak0.001
 Yes11 (20%)
 No44 (80%)

Re- exploration0.037
 Yes5 (9.1%)
 No50 (90%)

Drainage duration (days)0.001
 Mean12.11
 Range0–70

Complications0.8
 Clavien–Dindo III, IV12 (22%)
 Clavien–Dindo I, II22 (40%)

Mortality0.47
 Yes21 (38%)
 No34 (62%)