Research Article
Predicting Independence 6 and 18 Months after Ischemic Stroke Considering Differences in 12 Countries: A Secondary Analysis of the IST-3 Trial
| | Characteristics of sample participants vs. sample at 18 months | Baseline sample 3035, (%) | 18 months 2502, (%) | value |
| | Age | | | 0.95 | | 18-50 | 127 (4.2%) | 93 (3.7%) | | | 51-60 | 202 (6.7%) | 159 (6.4%) | | | 61-70 | 365 (12.0%) | 306 (12.2%) | | | 71-80 | 724 (23.9%) | 596 (19.6%) | | | 81-90 | 1407 (46.4%) | 1170 (46.8%) | | | > 91 | 210 (6.9%) | 178 (7.1%) | | | NHISS | | | 0.35 | | 0 (no clinical signs) | 1 (0.1%) | 1 (0.1%) | | 1-4 (light) | 399 (13.1%) | 306 (12.2%) | | 5-15 (mild to moderate) | 1665 (54.9%) | 1341 (53.6%) | | 16-20 (moderate) | 543 (17.9%) | 476 (19.0%) | | 21-42 (severe) | 427 (14.1%) | 378 (15.1%) | | Stroke subtype | | | 0.47 | | TACI | 1306 (43.0%) | 1129 (45.1%) | | PACI | 1146 (37.8%) | 913 (36.5%) | | LACI | 332 (10.9%) | 275 (11.0%) | | POCI | 246 (8.1%) | 180 (7.2%) | | Other | 5 (0.2%) | 5 (0.2%) | | Lived alone before the stroke | | | 0.73 | | Yes | 1129 (37.2%) | 942 (37.6% | | No | 1906 (62.8%) | 1560 (62.4%) | | Previous history of TIA/stroke | | | 0.81 | | Yes | 699 (23.0%) | 583 (23.3%) | | No | 2331 (76.8%) | 1914 (76.5%) | | Unknown | 5 (0.2%) | 5 (0.2%) | | Atrial fibrillation | | | 0.49 | | Yes | 914 (30.1%) | 755 (31.0%) | | No | 2121 (69.9%) | 1727 (69.0%) | | Intervention | | | 0.93 | | rt-PA | 1515 (49.9%) | 1246 (49.8%) | | Control | 1520 (50.1%) | 1256 (50.2%) | | Able to raise both arms | | | 0.04 | | Yes | 1351 (44.5%) | 1044 (41.7%) | | No | 1684 (55.5%) | 1458 (58.3%) | | Able to walk without help | | | 0.14 | | Yes | 487 (16.0%) | 365 (14.6%) | | No | 2548 (84.0%) | 2137 (85.4%) | | Country | | | <0.01 | | Australia | 179 (5.9%) | 177 (7.1%) | | Belgium | 73 (2.4%) | 70 (2.8%) | | Italy | 326 (10.7%) | 236 (9.4%) | | Norway | 204 (6.7%) | 199 (8.0%) | | Others | 80 (8.4%) | 58 (2.3%) | | Poland | 347 (11.4%) | 306 (12.2%) | | Portugal | 82 (2.7%) | 38 (1.5%) | | Sweden | 297 (9.8%) | 296 (11.8%) | | United Kingdom | 1447 (47.7%) | 1122 (44.8%) |
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NHISS: National Institutes of Health Stroke Scale; TACI: strokes of the anterior total circulation; PACI: infarctions of anterior partial circulation; LACI: lacunar infarcts; POCI: posterior circulation strokes; TIA/AVC: transient ischemic attack/stroke; rt-PA: recombinant intravenous tissue plasminogen activator. Others—including Austria, Canada, Mexico, and Switzerland. |
