Predicting Independence 6 and 18 Months after Ischemic Stroke Considering Differences in 12 Countries: A Secondary Analysis of the IST-3 Trial
Table 3
Characteristics of the survival participants.
Baseline Sample (), (%)
6 months (), (%)
18 months (), (%)
Independence
Dependence
Independence
Dependence
Age
18-50
127 (4.2%)
88 (69.3%)
35 (27.6%)
62 (66.7%)
25 (26.9%)
51-60
202 (6.7%)
125 (61.9%)
64 (31.7%)
99 (62.3%)
43 (27.0%)
61-70
365 (12.0%)
186 (51.0%)
129 (35.3%)
148 (48.4%)
93 (30.4%)
71-80
724 (23.9%)
278 (38.4%)
294 (40.6%)
185 (31.0%)
198 (33.2%)
81-90
1407 (46.4%)
385 (27.4%)
534 (38.0%)
239 (20.4%)
290 (24.8%)
> 91
210 (6.9%)
26 (12.4%)
76 (36.2%)
14 (7.9%)
31 (17.4%)
NHISS
0 (no clinical signs)
1 (0.1%)
—
—
—
—
1-4 (mild)
399 (13.1%)
313 (78.4%)
64 (16.0%)
217 (70.9%)
53 (17.3%)
5-15 (mild to moderate)
1665 (54.9%)
684 (41.1%)
669 (40.2%)
474 (35.3%)
402 (30.0%)
16-20 (moderate)
543 (17.9%)
69 (12.7%)
244 (44.9%)
42 (8.8%)
150 (31.5%)
21-42 (severe)
427 (14.1%)
22 (5.2%)
155 (36.3%)
14 (3.7%)
75 (19.8%)
Gender
Female
1570 (51.7%)
474 (30.2%)
616 (39.2%)
312 (24.0%)
376 (28.9%)
Male
1465 (48.3%)
614 (41.9%)
516 (35.2%)
435 (36.2%)
304 (25.3%)
Stroke subtype
TACI
1306 (43.0%)
203 (15.5%)
557 (42.6%)
138 (12.2%)
313 (27.7%)
PACI
1146 (37.8%)
534 (46.6%)
405 (35.3%)
356 (39.0%)
261 (28.6%)
LACI
332 (10.9%)
203 (61.1%)
103 (31.0%)
159 (57.8%)
64 (23.3%)
POCI
246 (8.1%)
145 (58.9%)
65 (26.4%)
91 (50.6%)
40 (22.2%)
Other
5 (0.2%)
3 (60%)
2 (40.0%)
3 (60%)
2 (40.0%)
Lived alone before the stroke
Yes
1129 (37.2%)
396 (35.1%)
418 (37.0%)
278 (29.5%)
244 (25.9%)
No
1906 (62.8%)
692 (36.3%)
714 (37.5%)
469 (30.1%)
436 (27.9%)
Previous history of TIA/stroke
Yes
699 (23.0%)
214 (30.6%)
271 (38.8%)
143 (24.5%)
159 (27.3%)
No
2331 (76.8%)
872 (37.4%)
860 (36.9%)
602 (31.5%)
521 (27.2%)
Unknown
5 (0.2%)
—
—
—
—
Atrial fibrillation
Yes
914 (30.1%)
212 (23.2%)
343 (37.5%)
130 (16.8%)
196 (25.3%)
No
2121 (69.9%)
876 (41.3%)
789 (37.2%)
617 (35.7%)
484 (28.0%)
Intervention
rt-PA
1515 (49.9%)
554 (36.6%)
553 (36.5%)
393 (31.5%)
320 (25.7%)
Control
1520 (50.1%)
534 (35.1%)
579 (38.1%)
354 (28.2%)
360 (28.7%)
Able to raise both arms
Yes
1351 (44.5%)
778 (57.6%)
404 (29.9%)
524 (50.2%)
246 (23.6%)
No
1684 (55.5%)
310 (18.4%)
728 (43.2%)
223 (15.3%)
434 (29.8%)
Able to walk without help
Yes
487 (16.0%)
357 (73.3%)
97 (19.9%)
240 (65.8%)
71 (19.5%)
No
2548 (84.0%)
731 (28.7%)
1035 (40.6%)
507 (23.7%)
609 (28.5%)
Country
Australia
179 (5.9%)
60 (33.5%)
69 (38.5%)
52 (29.4%)
61 (34.5%)
Belgium
73 (2.4%)
27 (37.0%)
25 (34.2%)
26 (37.1%)
17 (24.3%)
Italy
326 (10.7%)
111 (34.0%)
147 (45.1%)
64 (27.1%)
94 (39.8%)
Norway
204 (6.7%)
80 (39.2%)
76 (37.3%)
77 (38.7%)
59 (29.6%)
Others
80 (2.6%)
35 (43.8%)
21 (26.3%)
15 (25.9%)
15 (25.9%)
Poland
347 (11.4%)
186 (53.6%)
80 (23.1%)
141 (46.1%)
55 (18.0%)
Portugal
82 (2.7%)
20 (24.4%)
37 (45.1%)
3 (7.9%)
6 (15.8%)
Sweden
297 (9.8%)
134 (45.1%)
106 (35.7%)
122 (41.2%)
92 (31.1%)
United Kingdom
1447 (47.7%)
435 (30.1%)
572 (39.5%)
247 (22.0%)
281 (25.0%)
NHISS: National Institutes of Health Stroke Scale; TACI: strokes of the anterior total circulation; PACI: infarctions of anterior partial circulation; LACI: lacunar infarcts; POCI: posterior circulation strokes; TIA/AVC: transient ischemic attack/stroke; rt-PA: recombinant intravenous tissue plasminogen activator. Others: Austria, Canada, Mexico, and Switzerland were grouped into one group due to their small number of participants.
