Predicting Independence 6 and 18 Months after Ischemic Stroke Considering Differences in 12 Countries: A Secondary Analysis of the IST-3 Trial

Table 5

Final model for poststroke independence at 6 and 18 months.

	6 months ()		18 months ()
	OR (95% CI)		OR (95% CI)
Age (reference: >91)		<0.01		<0.01
18-50	5.65 (2.93-10.87)	<0.01	6.42 (2.66-15.50)	<0.01
51-60	3.99 (2.19-7.15)	<0.01	4.90 (2.17-11.04)	<0.01
61-70	3.01 (1.73-5.19)	<0.01	3.50 (1.63-7.51)	<0.01
71-80	2.34 (1.39-3.91)	<0.01	2.35 (1.13-4.90)	0.02
81-90	1.71 (1.03-2.84)	0.04	1.89 (0.92-3.87)	0.08
Gender (reference: female)
Male	—	—	1.44 (1.13-1.85)	<0.01
NHISS (reference: severe (21–42))		<0.01		<0.01
Mild (1–4)	7.33 (4.02-13.53)	<0.01	5.27 (2.49-11.15)	<0.01
Mild to moderate (5–15)	3.16 (1.92-5.20)	<0.01	2.99 (1.59-5.64)	<0.01
Moderate (16–20)	1.80 (1.06-3.05)	0.03	1.38 (0.70-2.73)	0.36
Stroke type (reference: TACI)		<0.01		<0.01
PACI	1.44 (1.12-1.85)	<0.01	1.30 (0.95-1.77)	0.10
LACI	2.03 (1.45-2.84)	<0.01	2.28 (1.52-3.43)	<0.01
POCI	1.76 (1.19-2.59)	<0.01	1.61 (0.99-2.62)	0.06
Others	0.41 (0.06-2.96)	0.38	0.43 (0.06-3.04)	0.40
Previous history of TIA/stroke (reference: yes)
No	1.28 (1.02-1.61)	0.04	—	—
Intervention (reference: no)
Yes	—	—	1.41 (1.11-1.79)	<0.01
I lived alone before the stroke (reference: no)
Yes	—	—	1.33 (1.03-1.73)	0.03
Able to raise both arms (reference: no)
Yes	2.10 (1.67-2.63)	<0.01	2.19 (1.65-2.91)	<0.01
Able to walk without help (reference: no)
Yes	2.05 (1.54-2.72)	<0.01	1.69 (1.19-2.39)	<0.01

NHISS: National Institutes of Health Stroke Scale; TACI: strokes of the anterior total circulation; PACI: infarctions of anterior partial circulation; LACI: lacunar infarcts; POCI: posterior circulation strokes; TIA/AVC: transient ischemic attack/stroke; OR: odds ratio; CI: confidence interval.