Genetic Evolution and Biological Characteristics of Feline Caliciviruses Isolated from Dogs
Table 2
Comparative analysis of genomic sequences of two canine-origin FCV isolates.
Origin
Strain
Canine/GXHC01-21 (nucleotide/amino acid)
Canine/GXNN10-21 (nucleotide/amino acid)
Genome
ORF1
ORF2
VP1-Ec
ORF3
Genome
ORF1
ORF2
VP1-Ec
ORF3
Canine
GXNN10-21
81.8
83.3/94.4
77.4/86.7
74.7
83.8/93.5
N/A
N/A
N/A
N/A
N/A
Feline
R-GX01-13
80.3
80.7/92.9
79.1/87.3
74.5
81.3/86.9
79.5
80.4/92.0
77.1/86.1
72.4
78.5/89.7
Feline
R-GXLZ01-19
82.1
84.0/95.4
77.1/87.7
80.6
82.9/91.6
83.9
85.9/95.0
82.0/92.4
73.5
88.8/98.1
Feline
R-GXNN01-19
82.5
84.6/95.1
77.3/88.1
77.6
81.3/88.8
85.6
86.0/95.7
84.2/93.1
86.7
88.8/95.3
Feline
E-GXNN04-20
84.3
87.2/96.7
77.0/87.3
77.6
82.9/92.5
83.9
83.7/93.9
84.0/92.8
82.7
88.8/99.1
Feline
E-GXNN05-20
83.1
83.8/95.0
80.4/89.4
73.5
87.2/95.3
83.5
86.2/95.7
76.1/87.0
74.5
83.5/95.3
Caninea
213/95
N/A
N/A
77.5/85.8
68.7
N/A
N/A
N/A
75.2/85.4
69.7
N/A
Canineb
10/Te/07
N/A
N/A
76.4/87.4
64.2
N/A
N/A
N/A
75.8/86.9
66.0
N/A
Vaccine
255
79.1
79.5/92.4
77.7/86.4
69.4
82.6/89.7
78.9
79.6/91.9
76.4/87.0
72.4
84.7/94.4
N/A represents not applicable; a the complete ORF2 gene sequence of the 213/95 strain isolated from a dog with diarrhea was obtained from GenBank database (AF283778); b the partial ORF2 gene sequence of the 10/Te/07 strain isolated from a dog with gastroenteritis was obtained from GenBank database (EU980610); c the identity of E region of VP1 protein between different strains at the amino acid level; R means respiratory origin; E means enteric origin. The FCV strain 255 is the commercial vaccine widely used in China.
