Based on the Results of PEDV Phylogenetic Analysis of the Most Recent Isolates in China, the Occurrence of Further Mutations in the Antigenic Site S1° and COE of the S Protein Which Is the Target Protein of the Vaccine

<div>The whole genome and S protein sequences of the CH/HLJBQL/2022 strain were analyzed for genetic evolution. (a) The CH/HLJBQL/2022 and 50 PEDV strains were subjected to evolutionary analysis and divided into two subtypes, GI and GII, with GII further subdivided into GIIa, GIIb, and GIIc. CH/HLJBQL/2022 is marked in red, and arrows indicate KUPE21 (MF737355.1) and CH/ZMDZY/11 (KC196276.1) as early fusion strains. (b) The evolutionary tree analysis of the S proteins of the 51 viruses was performed, and the results were generally consistent with the genome-wide evolutionary analysis.</div>

Transboundary and Emerging Diseases

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Figure 3: Based on the Results of PEDV Phylogenetic Analysis of the Most Recent Isolates in China, the Occurrence of Further Mutations in the Antigenic Site S1° and COE of the S Protein Which Is the Target Protein of the Vaccine 

Figure 3 | Based on the Results of PEDV Phylogenetic Analysis of the Most Recent Isolates in China, the Occurrence of Further Mutations in the Antigenic Site S1° and COE of the S Protein Which Is the Target Protein of the Vaccine 