Research Article

Characterization and Evaluation of the Pathogenicity of a Natural Gene-Deleted Transmissible Gastroenteritis Virus in China

Figure 5

The pathogenicity of TGEV on the newborn piglets. (a) The images of gross lesions. The gross lesions of lung, intestine, kidney, liver and spleen were observed at 96 hours post-infection. The black arrow points the gross lesions. (b) The viral-shedding of piglets after infected with TGEV. The viral-shedding were represented as log 10 copies per milliliter. (c) The viral loads of intestine, lung, kidney, liver and spleen. The viral loads were represented as log 10 copies per gram. Data were presented as mean ± SD (n = 5). , . (d) Histopathological analysis of luns, livers, spleen, kidney and intestine. The black arrow points thickening of the alveolar septa and fibrous exudation in the lung and villous atrophy and fusion in the intestine (hematoxylin and eosin staining, 200x magnification). (e) Analysis of lungs and intestine. The black arrow points TGEV (lung, 200x magnification; jejunum, 400x magnification).
(a)
(b)
(c)
(d)
(e)