An Inactivated Novel Trivalent Vaccine Provides Complete Protection against FAdV-4 Causing Hepatitis-Hydropericardium Syndrome and FAdV-8b/-11 Causing Inclusion Body Hepatitis

Figure 5

The representative gross lesion in the heart, liver, and kidney from chickens in each group after challenging with FAdV-4 (a), FAdV-8b (b), and FAdV-11 (c). (a) Chickens in the unvaccinated and FAdV-4 challenge group showed accumulation of clear straw-colored fluid in the pericardial sac, swollen and discolored liver, and enlarged kidneys with distended tubules. (b) and (c) Chickens in the FAdV-8b or FAdV-11 challenge control group exhibited IBH-indicative gross lesions, characterized by swollen livers with small white focal necrosis and petechial hemorrhages.

(a)

(b)

(c)