Research Article

Experimental Inoculation of Porcine Circovirus 3 (PCV-3) in Pregnant Gilts Causes PCV-3-Associated Lesions in Newborn Piglets that Persist until Weaning

Figure 5

(a) Lung section with histologically normal hyaline cartilage in the bronchi (H&E). (b) PCV-3 ISH of the same section, revealing labelled chondrocytes (hematoxylin counterstain). (c) Histologically normal lymph node (H&E). (d) PCV-3 ISH of the same lymph node, revealing abundant PCV-3 genome within follicles and in parafollicular areas, especially in subcapsular sinuses (hematoxylin counterstain). (e) Prominent lymphoid follicle, histologically normal (H&E). (f) Same lymphoid follicle by PCV-3 ISH, revealing intense positive signal (hematoxylin counterstain).