Experimental Inoculation of Porcine Circovirus 3 (PCV-3) in Pregnant Gilts Causes PCV-3-Associated Lesions in Newborn Piglets that Persist until Weaning
Table 1
Proportion and percentage of piglets displaying histopathological lesions in each tissue for each group and time point.
Lesion
T1F
T1W
T2F
T2W
T3F
T3W
PA-mesenterium
10/33 (30.3%)
19/32 (59.4%)
0/27 (0%)
4/23 (17.4%)
0/8 (0%)
0/9 (0%)
PA-kidney
1/33 (3.0%)
13/32 (40.6%)
0/27 (0%)
2/23 (8.7%)
0/8 (0%)
0/9 (0%)
PA-spleen
3/33 (9.1%)
14/32 (43.8%)
0/27 (0%)
3/23 (13.0%)
0/8 (0%)
0/9 (0%)
PA-meninges
0/0 (0%)
12/32 (37.5%)
0/27 (0%)
0/23 (0%)
0/8 (0%)
0/9 (0%)
PA-lung
0/0 (0%)
5/31 (16.1%)
0/27 (0%)
1/23 (4.3%)
0/8 (0%)
0/9 (0%)
PA-heart
0/0 (0%)
6/31 (19.4%)
0/27 (0%)
0/23 (0%)
0/8 (0%)
0/9 (0%)
PA–liver
0/0 (0%)
5/32 (15.6%)
0/27 (0%)
0/23 (0%)
0/8 (0%)
0/9 (0%)
Lymphohistiocytic myocarditis
3/33 (9.1%)
16/31 (51.6%)
0/27 (0%)
0/23 (0%)
0/8 (0%)
0/9 (0%)
Interstitial pneumonia
1/33 (3.0%)
14/31 (45.2%)
0/27 (0%)
6/23 (26.1%)
0/8 (0%)
0/9 (0%)
Nonsuppurative encephalitis
8/33 (24.2%)
18/32 (56.3%)
0/27 (0%)
0/23 (0%)
1/8 (12.5%)
0/9 (0%)
Interstitial nephritis
3/33 (9.1%)
3/32 (9.4%)
0/27 (0%)
2/23 (8.7%)
0/8 (0%)
0/9 (0%)
F, farrowing; W, weaning; PA, periarteritis; T1, piglets from gilts inoculated during the second third of gestation; T2, piglets from gilts inoculated during last third of gestation; T3, piglets from control, non-inoculated gilts.
