Exploring Appropriate Strategies for Vaccination against Classical Swine Fever under a Dynamic Change in Antibody Titer in Sows after Starting Vaccination in a Japanese Farm Setting

Figure 3

Scheme for simulating antibody dynamics among different generations of pigs: (a) the antibody titers of the first generation of sows (G₁, 30 individuals) in our simulation were determined by random sampling of the observed S/P ratio data; (b) the titers of maternally derived antibodies (MDAs) of the second generation (G₂, 360 animals; 12 from each G₁ sow) were predicted from the antibody titers of the G₁ sows; (c) the vaccine-induced antibody (VIA) titers until the slaughter age (26 weeks) were predicted; (d) 30 sow candidates were randomly resampled as sows for the next generation. The antibody titers of G₃ were predicted based on those of G₂, and the prediction was repeated up to G₅.