Retrospective Detection and Phylogenetic Analysis of Cachavirus-Related Parvoviruses in Dogs in China

Table 2

Details of the main amino acid mutation sites in the NS1 and VP1 proteins of cachavirus in Chinese (“CHN-”; this study) compared with reference strain (IDEXX1).

Strains

Substitution of amino acid residues

NS1

VP1

252

253

254

255

328

426

457

603

607

622

186

265

449

470

493

IDEXX1

S

G

G

Y

F

D

D

G

R

K

A

V

R

K

V

CN20181128

C

L

T

F

F

D

N

R

G

K

A

V

R

R

V

CN20190714

C

L

T

F

F

D

N

R

G

K

A

I

K

K

I

CN20190806

S

V

T

F

F

D

D

R

G

K

A

V

R

K

V

CN20190917

S

V

T

F

F

D

N

R

G

K

A

V

R

K

V

CN20191013

S

V

T

F

F

D

N

R

G

K

A

I

R

K

V

CHC181031

C

L

T

F

F

D

N

R

G

K

A

I

K

K

V

CHC190520

S

V

T

F

F

D

N

R

G

K

A

I

K

K

I

CHN1601

S

V

T

F

F

D

D

R

G

R

A

I

K

K

I

CHN1602

S

V

T

F

F

N

N

R

G

K

P

I

R

K

V

CHN1703

S

V

T

F

S

N

D

R

G

K

A

V

R

K

V

CHN1704

C

L

T

F

F

D

N

R

G

R

P

I

R

R

V