Research Article

Rapid Discrimination of Pseudomonas aeruginosa ST175 Isolates Involved in a Nosocomial Outbreak Using MALDI-TOF Mass Spectrometry and FTIR Spectroscopy Coupled with Machine Learning

Figure 2

Classification of MALDI-TOF MS spectra between “outbreak” and “not outbreak” isolates. (a) Hierarchical clustering analysis with Euclidean distance and ward metric, (b) principal component analysis, and (c) differentiation of WGS-groups by PLS-DA (partial least squares discriminant analysis) algorithm. MALDI-TOF MS, matrix-assisted laser desorption ionization–time of flight mass spectrometry; WGS, whole-genome sequencing.
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