Plasma Proteome-Wide Mendelian Randomization Analysis Reveals Biomarkers and Therapeutic Targets for Different Stages of COVID-19

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Protein</td><td class="align_center">Odds ratio</td><td class="align_center">95% CI</td><td class="align_center"><i>P</i> value</td><td class="align_center">Cis/pan</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">PCNP</td><td class="align_center">0.683</td><td class="align_center">0.612–0.763</td><td class="align_center">1.221e-11</td><td class="align_center">Cis</td></tr><tr><td class="align_left">BCAT2</td><td class="align_center">1.151</td><td class="align_center">1.074–1.234</td><td class="align_center">7.358e-05</td><td class="align_center">Cis</td></tr><tr><td class="align_left">PCNP</td><td class="align_center">0.683</td><td class="align_center">0.612–0.763</td><td class="align_center">1.221e-11</td><td class="align_center">Pan</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Potential causal proteins for SARS-CoV-2 infection identified in the cis- and pan-analyses.</div>

Transboundary and Emerging Diseases

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Table 4

Table 4: Plasma Proteome-Wide Mendelian Randomization Analysis Reveals Biomarkers and Therapeutic Targets for Different Stages of COVID-19 