Potential Pathogenicity and Genetic Characteristics of a Live-Attenuated Classical Swine Fever Virus Vaccine Derivative Variant

Figure 1

The clinical information of the pig farm and phylogenetic analysis of the CSFV isolates. (a) Mummies, rotten, and white fetuses were observed when the sows began to deliver. (b) The immune procedure in the pig farm. PPV: WH-1 strain, inactivated vaccine; JEV: SA14-14-2 strain, live-attenuated vaccine; PRV: Batha-K61 strain, live-attenuated vaccine; CSFV: cell culture adapted C-strain, live-attenuated vaccine; PCV2: recombinant vaccine. (c) Phylogenetic analysis based on polyprotein nucleotide sequences of CSFVs. The phylogenetic tree was inferred using MEGA 11.0 with the neighbor-joining method. The CSFV isolate CSFV/HeNLY2022 was marked by a black solid circle (●). The live-attenuated prototype strain C/HVRI (GenBank no. AY805221) was indicated by a triangle symbol (▲).

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