Pathogenesis, Transmission, and Within-Host Evolution of Bovine-Origin Influenza D Virus in Pigs

Figure 4

Numbers of reads (WGS) exhibiting the HEF-L118F substitution in deduced amino acid sequences of bovine IDV inoculum (P0) and swine IDV strains obtained after 1, 2, or 3 passages on pigs. Gray bars represent numbers of reads with L118F substitution, and white bars represent numbers of reads without this substitution. The percentages (%) are the proportions of HEF reads with L118F substitution. P0 = without passage on pig; P1 = first passage on pig; P2 = second passage on pig; P3 = third passage on pig.