Research Article

First Report and Genetic Characterization of Border Disease Virus in Sheep from Hulunbuir, Northeastern China

Table 1

Comparison of predicted border disease virus (BDV) polyprotein cleavage sites.

VirusCleavage site at
Npro/C C/ErnsErns/E1E1/E2E2/P7P7/NS2NS2/NS3NS3/NS4ANS4A/NS4BNS4A/NS5A

TSC/SDDVAP/ENVANA/QSPAQG/QFATSA/INLVKG/EGAILR/GPATGL/SAAKEL/AQGRRL/SGN
…/….TS/……/……/……/MT.…/D..…/……/……/….S./…
…/….KP/..I…/….K./E..…/MS.…/D..…/……/.T.…/….S./…
…/….TP/..I.Y./……/……/MS.…/D..…/……/……/….N./…
…/……/..I…/……/…A../MC.…/D.T…/……/……/…. S./…
…/……/..I…/……/……/MS.…/……/……/.T.…/….S./…
…/…A.A/..I…/……/…A../MG.…/.ET…/……/……/….N./…
…/….SM/..I…/……/…A../MG.…/.ET…/……/.T.…/….N./…
…/….SM/..I…/……/…A../MG.…/.ET…/……/.T.…/….N./…
…/….S./..I…/……/…A../KGF.R./.ET…/…A../……/….N./…
…/….LS/..I…/….N./..SAA./MS..R./.ET…/……/……/….N./…
…/….TS/..I…/……/…A../VS.…/SDV…/…A../……/….N./…
…/….TS/..I…/……/…A../VS.…/SDV…/…A../……/….N./…
…/….TS/..I…/……/..TA../SG.…/SEV…/…S../.T.…/….N./…
A../….TS/..I…/……/.L.A../LS.…/SEV…/……/……/….N./…
…/….T./..I…/……/….T./MS..R./AEV…/……/……/….N./…
…/…TSS/..I…/……/…AN./.S.…/AET…/……/……/….N./…
…/..E.TS/..I…/.T.…/..TAA./.S.…/.QE…/…A../……/….T./.S.

Slashes (/) indicate cleavage. The BDV strains marked with different colors indicate different genotypes of BDV. BDV-1 (Orange), BDV-2 (Cyan), BDV-3 (Yellow), BDV-4 (Blue), BDV-5 (Brown), BDV-7 (Purple), BDV-8 (Green). BDV-6 was not listed in the table due to the need for a complete genome. OQ378958 marked with red color was the BDV strain identified in this study.