Differences of Clinicopathological Features between Metaplastic Breast Carcinoma and Nonspecific Invasive Breast Carcinoma and Prognostic Profile of Metaplastic Breast Carcinoma
Table 1
General characteristics of MBC and NSIBC.
Category
NSIBC (n = 433)
MBC (n = 34a)
X 2
-value
Median age in years (IQR)
50.00 (44.00∼56.00)
49.50 (44.00∼56.00)
0.005
0.9963
BMI (kg/m2, IQR)
24.00 (22.20∼26.30)
24.15 (22.40∼26.70)
0.354
0.7235
Site of lesion
Left
209.00 (48.27%)
22.00 (64.71%)
3.4077
0.065
Right
224.00 (51.73%)
12.00 (35.29%)
Smoking history
5.00 (1.15%)
0.00 (0.00%)
—
1.000
Drinking history
6.00 (1.39%)
1.00 (2.94%)
—
0.413
Family history
21.00 (4.85%)
1.00 (2.94%)
—
1.000
Menopause
184.00 (42.49%)
12.00 (35.29%)
0.6710
0.413
Hypertension
66.00 (15.24%)
3.00 (8.82%)
1.0315
0.310
Diabetes
20.00 (4.62%)
1.00 (2.94%)
—
1.000
Hyperlipidemia
62.00 (14.32%)
4.00 (11.76%)
—
1.000
T Category of the primary tumor (AJCC 8thb)
T1
235.00 (54.27%)
10.00 (29.41%)
3.254
0.0011
T2
176.00 (40.65%)
18.00 (52.94%)
T3
15.00 (3.46%)
2.00 (5.88%)
T4
7.00 (1.62%)
4.00 (11.76%)
Lymph node status
199.00 (46.06%)
15.00 (44.12%)
0.0481
0.826
Skin or chest wall invasion
7.00 (1.62%)
4.00 (11.76%)
—
0.005
Vessel carcinoma embolus
87.00 (20.09%)
5.00 (14.71%)
0.5782
0.447
Surgical treatmentc
Lumpectomy
83.00 (19.17%)
7.00 (18.92%)
0.0014
0.970
Mastectomy
350.00 (80.83%)
30.00 (81.08%)
a. Among 37 cases of MBC, 34 cases had complete medical history materials. b. The 8th version of the America Joint Committee on Cancer (AJCC) staging system. c. In 37 cases of MBC, all cases received surgical treatments. MBC: metaplastic breast carcinoma; NSIBC: nonspecific invasive breast carcinoma; BMI: body mass index; IQR: interquartile range.
