Research Article
Differences of Clinicopathological Features between Metaplastic Breast Carcinoma and Nonspecific Invasive Breast Carcinoma and Prognostic Profile of Metaplastic Breast Carcinoma
Table 2
Clinicopathological features of MBC and NSIBC.
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a. Among 37 cases of MBC, 34 cases had complete medical history materials. b. In 37 cases of MBC, 33 cases could obtain the level of Her-2, and 34 cases could obtain the expression levels of ER, PR, and Ki-67. c. According to the guidelines of the Chinese Society of Clinical Oncology in 2020, the minimum positive threshold of ER, PR, and Ki-67 were 1%, 1%, and 14%, respectively, and Her-2 (3+) or ISH positivity meant Her-2 positivity. Breast cancer was divided into luminal A (ER/PR positive, Her-2 negative with low Ki-67 index) disease, luminal B (ER/PR positive, Her-2 negative with high Ki-67 index, or ER/PR positive and Her-2 positive) disease, Her-2 positive (ER and PR negative and Her-2 positive) disease, and triple-negative (ER, PR, and Her-2 negative) disease according to molecular subtyping. MBC: metaplastic breast carcinoma; NSIBC: nonspecific invasive breast carcinoma; ER: estrogen receptor; PR: progesterone receptor; Her-2: human epidermal growth factor receptor 2. |