Research Article

Analysis of Clinicopathological Characteristics and Prognosis of Carcinosarcoma of the Breast

Table 1

Clinicopathological features and treatment modalities in patients with carcinosarcoma of the breast.

CharacteristicsNumber of patients%

Age
 ≤502144.7
 >502655.3
Menopausal status
 Premenopausal2246.8
 Postmenopausal2553.2
TI (D)
 <1803574.5
 ≥1801225.5
Tumor size
 <5 cm3574.5
 ≥5 cm1225.5
T stage at diagnosis
 T1919.1
 T22655.3
 T31021.3
 T424.3
N stage at diagnosis
 N03983.0
 N1817.0
Estrogen-receptor status
 Positive00.0
 Negative4697.9
 Unknown12.1
Progesterone-receptor status
 Positive36.4
 Negative4391.5
 Unknown12.1
HER2/neu (IHC and/or FISH) status
 Positive12.1
 Negative4595.7
 Unknown12.1
EGFR status
 Positive1634.0
 Negative48.5
Unknown2757.5
Therapeutic method
 Surgery only2144.7
 Comprehensive therapy2655.3
Breast surgery
 Radical mastectomy612.8
 Modified radical mastectomy3778.7
 Lumpectomy48.5
Neoadjuvant chemotherapy
 Yes36.4
 No4493.6
Adjuvant chemotherapy
 Yes2246.8
 No2553.2
Adjuvant radiation therapy
 Yes48.5
 No4391.5
Adjuvant hormonal therapy
 Yes00.0
 No47100.0

TI: time interval between first discomfort and first consultation; HER2: epidermal growth factor receptor 2; IHC: immunohistochemistry; FISH: fluorescent in situ hybridization technique; EGFR: epidermal growth factor receptor.