RBM8A Depletion Decreases the Cisplatin Resistance and Represses the Proliferation and Metastasis of Breast Cancer Cells via AKT/mTOR Pathway

Table 2

Correlation between RBM8A expression and clinicopathological features in breast cancer patients.

Characteristics	Total n = 70	RBM8A expression		-value
		Low (n = 35)	High (n = 35)
Age				0.473
≤45	37	20	17
>45	33	15	18
Tumor size				0.334
≤2 cm	40	22	18
>2 cm	30	13	17
PR status				0.632
Negative	36	17	19
Positive	34	18	16
HER-2 status				0.626
Negative	42	20	22
Positive	28	15	13
TNM stage				0.004
I/II	38	13	25
III/IV	32	22	10
Lymph node metastasis				0.039
Negative	48	28	20
Positive	22	7	15

Note. , . PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2; TNM, tumor-node-metastases; RBM8A, RNA Binding Motif Protein 8A.