Breast Cancer Patients with Brain Metastases: A Cross-Sectional Study

Table 1

Clinical and histopathological characteristics of the patients.

Characteristics		Mean ± SD	Min-max (median)
Age (years)		48.09 ± 11.21	22–73 (46,6)
Overall survival (months)		58.55 ± 51.09	1.8–356 (45.6)
Survival after BM (months)		12.98 ± 16.96	0–94 (7.26)
		n	%
Sites of metastasis at BM development	Only BM	23	18.1
	BM + bone	27	21.3
	BM + visceral	77	60.6
Number of BM	Only 1	41	32.3
	2	10	7.9
	>2	58	45.7
	Leptomeningeal	18	14.2
Metastasectomy	Yes	19	15
	No	108	85
Radiotherapy	Whole brain radiotherapy	90	95.7
	Gamma knife	4	4.3
Histology	Invasive ductal	117	92.1
	Invasive lobular	7	5.5
	Others	3	2.4
Receptor status	ER or PR positive	80	63
	ER and PR negative	47	37
HER-2 status	HER-2 positive	45	35.4
	HER-2 negative	82	64.6
Breast cancer subtype	Luminal A	8	6.3
	Luminal B	72	56.7
	HER-2 overexpressing	21	16.5
	Triple negative	26	20.5
Total		127	100

BM: brain metastasis; ER: estrogen receptor; PR: progesterone receptor.