Research Article

Evaluation of Axillary Lymph Node Marking with Magseed® before and after Neoadjuvant Systemic Therapy in Breast Cancer Patients: MAGNET Study

Table 1

Patient characteristics.

CharacteristicsOverall (%)Patients (Post-NAST) (%)Patients (Pre-NAST) (%)

Number of patients (n)81 (100)37 (45.7)44 (54.3)
Age
 Mean (SD)50.7 (12.7)50.9 (10.9)50.6 (14.1)
 95% CI(48.0; 53.5)(47.4; 54.4)(46.4; 54.7)
 Median (min; max)47.0 (29.0; 78.0)47.0 (33.0; 78.0)47.0 (29.0; 74.0)
 P25; P7541.0; 61.044.0; 56.040.0; 63.8
Initial tumor size (cm)
 Mean (SD)4.0 (2.9)3.4 (2.1)4.5 (3.4)
 95% CI(3.4; 4.7)(2.8; 4.1)(3.5; 5.6)
 Median (min; max)3.1 (0.0; 16.0)2.8 (0.0; 9.1)3.2 (1.5; 16.0)
 P25; P752.3; 5.32.3; 3.62.6; 5.6
Initial lymph node staging
 cN181 (100)37 (100)44 (100)
Tumor pathological response (Post-NAST)
 Patients793643
 pPR45 (56.9)18 (50.0)27 (62.8)
 pCR34 (43)18 (50.0)16 (37.2)
Surgical procedure on the breast
 Patients813743
 BCS51 (62.9)26 (70.3)25 (58.1)
 MT30 (37)11 (29.7)18 (41.9)
Molecular classification
 Patients813744
 HER + EP+27 (33.3%)17 (45.9%)10 (22.7%)
 LB41 (50.7%)16 (43.3%)25 (56.9%)
 TN10 (12.3%)4 (10.8%)6 (13.6%)
 LA2 (2.5%)0 (0%)2 (4.5%)
 LB/HER2+1 (1.2%)0 (0%)1 (2.3%)

Information missing for 2 cases. BCS, breast-conserving surgery; EP, estrogen and progesterone receptor; HER2 human epidermal growth factor receptor; LA, luminal A; LB, luminal B; MT, mastectomy; NAST, neoadjuvant systemic therapy; pCR, pathological complete response; pPR, pathological partial response; TN, triple negative.