Research Article

Preserving Nipple Sensitivity after Breast Cancer Surgery: A Systematic Review and Meta-Analysis

Table 3

Objective outcomes and sensory testing.

LocationPopulationStudies reportedStudies reportedNo. of breastsAverage SWM valueTotal breastsWeighted average SWM valueSensory perception

NippleNSM4Tevlin (NSM)204.91384.7Loss of protective sensation
Pek154.435
Tomita (BCS)473.84
Tomita (SSM)204.56
van Verschuer365.814
nNSM1Tevlin (nNSM)143.9143.9Diminished light touch to diminished protective sensation
Non-op control4Tevlin (nNSM control)143.21952.9Normal to diminished light touch
Tevlin (NSM control)202.83
Pek153.142
Tomita1042.83
van Verschuer422.908

AreolaNSM3Tevlin (NSM)205.68715.5Loss of protective sensation
Pek154.41
van Verschuer365.76
nNSM1Tevlin (nNSM)144.84144.8Loss of protective sensation
Non-op control2Pek152.908573.1Normal to diminished light touch
van Verschuer423.123

BCS, breast-conserving surgery; NSM, nipple-sparing mastectomy; nNSM, nipple-sparing mastectomy with neurotization of nipple-areola complex; non-op, not operated; SSM, skin-sparing mastectomy; SWM, Semmes–Weinstein monofilaments.