Clinical Study
Pro- and Antiapoptotic Markers in Upper Tract Urothelial Carcinoma
Associated with Balkan Endemic Nephropathy
Figure 1
The representative immunohistochemical staining of apoptotic markers in BEN-associated urothelial carcinoma, with strong nuclear Survivin activity in high grade (a) and tumors with solid growth (b), diffuse Bax cytoplasm expression (c), membranous Fas staining in nonmetaplastic BEN-related tumors (d). Rarely Bcl-2 positive tumor cells (e). Caspase 3 expression in a high-grade tumor (f) (original magnification: x400).