Activation of <i>β</i>-Adrenoceptors by Dobutamine May Induce a Higher Expression of Peroxisome Proliferator-Activated Receptors <i>δ</i> (PPAR<i>δ</i>) in Neonatal Rat Cardiomyocytes

<table><i>Effects of dobutamine on PPAR<i>δ</i> expression in neonatal rat cardiomyocytes</i>. The neonatal rat cardiomyocytes were treated with dobutamine at various concentrations for 4 hours (a) or at 1 <i>μ</i>mol/L during various time points (b). The treated cells were harvested to determine the protein levels by Western blotting analysis. All values are presented as mean ± SEM (<svg height="11.0375" id="M4" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 35.099998 11.0375" width="35.099998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.0375)">
<g transform="translate(72,-63.17)">
<text transform="matrix(1,0,0,-1,-71.95,63.4)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑛</tspan>
<tspan style="font-size: 12.50px; " x="9.6773224" y="0">=</tspan>
<tspan style="font-size: 12.50px; " x="21.71771" y="0">6</tspan>
</text>
</g>
</g>
</svg> per group). <svg height="11.9" id="M5" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 62.487499 11.9" width="62.487499" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.9)">
<g transform="translate(72,-62.48)">
<text transform="matrix(1,0,0,-1,-71.95,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-66.87,62.83)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">5</tspan>
</text>
</g>
</g>
</svg> and **<svg height="11.0625" id="M6" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 56.150002 11.0625" width="56.150002" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.0625)">
<g transform="translate(72,-63.15)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">1</tspan>
</text>
</g>
</g>
</svg> as compared with the vehicle-treated control group.</table>

The Scientific World Journal

fig1

Figure 1

Figure 1: Activation of <i>β</i>-Adrenoceptors by Dobutamine May Induce a Higher Expression of Peroxisome Proliferator-Activated Receptors <i>δ</i> (PPAR<i>δ</i>) in Neonatal Rat Cardiomyocytes 

Figure 1 | Activation of β-Adrenoceptors by Dobutamine May Induce a Higher Expression of Peroxisome Proliferator-Activated Receptors δ (PPARδ) in Neonatal Rat Cardiomyocytes 