Acceleration of Anaerobic Cysteine Transformations to Sulfane Sulfur Consequent to 𝜸-Glutamyl Transpeptidase Inhibition

Figure 1

Reactive oxygen species (a), nonprotein sulfhydryl groups (b), cysteine (c) level, and γ-glutamyltranspeptidase activity (d) in healthy and Ehrlich ascites tumor- (EAT-) bearing mice livers, kidneys, and EAT cells. 0.9% NaCl (control groups), 1,2,3,4-tetrahydroisoquinoline (TIQ) at 50 mg·kg⁻¹ of body weight, and acivicin (AC) at 18 mg·kg⁻¹ were i.p. injected for 5 days. *-𝑃<0.05 versus control, **-𝑃<0.01 versus control, ***-𝑃<0.001 versus control, ^•-𝑃<0.05 versus NaCl, ^••-𝑃<0.01 versus NaCl, ^•••-𝑃<0.001 versus NaCl.

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