Polymerized-Type I Collagen Downregulates Inflammation and Improves Clinical Outcomes in Patients with Symptomatic Knee Osteoarthritis Following Arthroscopic Lavage: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial

Table 1

Demographic characteristics of the patients.

	Healthy control (𝑛=13)	Placebo (𝑛=9)	Polymerized-type I collagen (𝑛=10)
		Baseline	Baseline
Age (years); Mean ± SD	42.0 ± 8.1	57.0 ± 8.1	59.9 ± 9.7
Median	42.0	53.0	56.5
Range	(40.0–54.0)	(50.0–74.0)	(50.0–75.0)
Gender (female/male)	11/2	6/3	8/2
Disease duration (years); mean ± SD		6.4 ± 3.4	4.0 ± 3.5
Median		5.0	2.0
Range		(3.0–11.0)	(0.7–10.0)
OA grade (n)		III (1)	III (3)
		IV (8)	IV (7)
Body mass index (kg m^−2); mean ± SD	21.5 ± 1.6	30.7 ± 6.3	28.4 ± 3.9
Median	21.4	27.9	28.8
Range	(18.9–24.2)	(26.9–40.0)	(20.4–32.9)