A Study of Epstein-Barr Virus BRLF1 Activity in a Drosophila Model System

Table 1

Candidate gene screen of tumor suppressors.

Allele	Nature of allele*	Effect
14-3-3zeta^P1375	P element insertion	Enhancer of R
brat^1, brat ^k06028	EMS, P element insertion	Enhancer of R
Csk^c04256	P element insertion	Enhancer of R
GMR-E2F	Overexpresser	Enhancer of R
InR^E19	EMS	Enhancer of R
Merlin^4	loss of function	Enhancer of R
Rab5^EY10619	P element enhancer upstream,	Enhancer of R
Rab5^KG05684	P element insertion	Enhancer of Z (Rab5^EY10619 only)
ago^EY19092	P element insertion	Enhancer of Z
dlg1^G0276	P element insertion	Enhancer of Z
GMR-p53	Overexpresser	Enhancer of Z
		Suppressor of R
GMR-reaper	Overexpresser	Enhancer of Z
		Suppressor of R
Ras85^e1B	EMS missense mutation	Enhancer of Z
Tor^DeltaP, Tor^k17004	Deletion, P element insertion	Enhancer of Z
		Suppressor of R
awd^j2A4	P element insertion	Suppressor of R
chico^KG00336	P element insertion	Suppressor of R
GMR-dacapo	Overexpresser	Suppressor of R
GMR-Rbf	Overexpresser	Suppressor of R
scrib^j7b3	Hypomorph	Suppressor of R
hyd^15	EMS	Suppressor of Z
l(2)gd1^EY04750	P element insertion	Suppressor of Z
14-3-3epsilon^s-969	antimorph	Suppressor of Z

*Information about alleles from FlyBase.
EMS: ethyl methanesulfonate; hypomorph: less protein activity; antimorph: dominant negative protein activity.