Different Modulating Effects of Adenosine on Neonatal and Adult Polymorphonuclear Leukocytes
Figure 2
The modulating effects of adenosine on chemotaxis of neonatal and adult PMNs. (a) Cord blood PMNs always had a lower chemotactic ability than adult PMNs upon fMLP stimulation. The results are representative of 6 duplicate experiments. (b) Plots illustrate chemotactic ability (expressed as numeral of number relative to adenosine 0 μM in the ordinate) of adult and cord blood PMNs. The chemotactic ability of adult PMNs was decreased by about 40% at an adenosine concentration of 0.1 μM (compared with adenosine 0 μM). Data are expressed as mean ± SE. Abbreviations: AB PMNs: adult peripheral blood polymorphonuclear cells; CB PMNs: cord blood polymorphonuclear cells. Data presented are calculated from 6 duplicate experiments. as compared with adenosine 0 μM.
