Factors Predicting Ventilator Dependence in Patients with Ventilator-Associated Pneumonia

Table 3

Ventilator-associated pneumonia related characteristics^a.

Characteristics	Ventilator independence	Ventilator dependence	𝑃 value
	𝑁=36	𝑁=54
Ventilation day before VAP^b	9.58 ± 4.66^c	10.76 ± 5.44^c	0.29
Organism, number (%)
P. aeruginosa	13 (36)^c	25 (46)^c	0.34
A. baumannii	8 (22)^c	14 (26)^c	0.69
S. maltophilia	4 (11)^c	12 (22)^c	0.18
K. pneumoniae	4 (11)^c	9 (17)^c	0.46
S. aureus	9 (25)^c	13 (24)^c	0.92
Polymicrobial infection, number (%)	11 (31)^c	21 (39)^c	0.42
CPIS^b	8.64	8.83	0.45
BAL^b, number (%)	10 (28)^c	25 (46)^c	0.08
Appropriateness of initial empiric antibiotic, number (%)			<0.001
Appropriate	30 (83)^c	20 (37)^c
Inappropriate	1 (3)^c	22 (41)^c
Indeterminate	5 (14)^c	12 (22)^c
Initial Fi02^b (%)	41.31 ± 8.24^c	48.43 ± 12.09^c	0.003
Initial MAP^b	18.78 ± 5.45^c	23.01 ± 6.71^c	0.002
Initial OI^b	7.81 ± 3.55^c	14.19 ± 7.34^c	<0.001
Initial Pa02^b	105.36 ± 43.52^c	103.89 ± 45.46^c	0.88
Initial vital sign
Temperature	37.74 ± 1.35^c	38.34 ± 3.86^c	0.31
Respiratory rate	23.04 ± 8.21^c	19.76 ± 4.99^c	0.02
Heart rate	98.86 ± 28.14^c	95.91 ± 19.43^c	0.56
Mean blood pressure	85.31 ± 16.56^c	89.70 ± 5.52^c	0.25

^aContinuous variables were analyzed by Student’s 𝑡-test or Mann-Whitney 𝑈 test, and categorical data by chi-square test.
^bBAL: bronchoalveolar lavage, CPIS: Clinical Pulmonary Infection Score; FI02: fraction inspired oxygen, MAP: mean airway pressure, OI: oxygenation index, Pa02: arterial oxygen tension, VAP: ventilator associated pneumonia.
^cVariables are expressed as mean (standard deviation) and categorical data are expressed as number (percentage).