The Scientific World Journal / 2012 / Article / Tab 2 / Research Article
Large Scale Association Analysis for Drug Addiction: Results from SNP to Gene Table 2 Summary of the candidate genes identified by the gene-based and SNP-based methods.
Chr Gene Source P value (gene-based)a Min P value (SNP-based)b Detected SDc Reported SD Reference 1 KIAA0040 White women
Alcohol Alcohol [27 , 44 ] 2 HAAO White women
Cocaine Alcohol [41 ] 2 NCK2 Black men
Opiates NA NA 3 SH3BP5 White men
Cocaine Alcohol [13 ] 4 MANBA White men
Alcohol Alcohol [29 ] 7 RELN White men
Cocaine Smoking [37 ] 8 CSMD1 Black women
Nicotine Smoking [37 , 38 ] 11 LRP5 White men
Opiates Smoking [42 ] 11 PKNOX2 White women
Alcohol Alcohol [13 , 27 , 41 ] 12 IFNG White women
Opiates Smoking [37 ] 18 FAM38B Black women
Cocaine Smoking [40 ] 18 PTPRM Black women
Marijuana Alcohol [43 ] 22 MAPK1 Black women
Marijuana Alcohol [25 ]
a P value (gene-based): the P value obtained by the gene-based association test;
b min P value (SNP-based): the minimal P value of the SNPs within the corresponding gene;
c SD: substance dependence.