| | Group | 1 () | 2 () | 3 () | |
| | Age, years, mean (SD) | 50.5 (15.6) | 50.9 (11.4) | 46.9 | 0.209 | | Men, (%) | 11 (35.5) | 26 (47.3) | 24 (43.6) | 0.569 | | History of hypertension, years, mean (SD) | 5.2 (5.0) | 8.0 (7.6) | 6.6 (7.8) | 0.251 | | Body weight, kg, mean (SD) | 62.7 (12.0) | 67.2 (14.0) | 66.9 (13.0) | 0.293 | | Body height, cm, mean (SD) | 162.2 (9.7) | 161.0 (8.3) | 161 (8.8) | 0.744 | | Body mass index, kg/m2, mean (SD) | 23.7 (2.6) | 25.9 (4.0)† | 25.7 | 0.019 | | Blood urea nitrogen, mg/dL, mean (SD) | 13.6 (3.1) | 14.0 (4.2) | 12.1 | 0.052 | | Creatinine, mg/dL, mean (SD) | 0.94 (0.17) | 0.97 (0.23) | 0.91 (0.24) | 0.472 | | SBP, mmHg, mean (SD) | 146 (17) | 152 (22) | 153 (22) | 0.293 | | DBP, mmHg, mean (SD) | 87 (11) | 94 (13)† | 93 (14) | 0.056 | | Serum potassium, mEq/L, mean (SD) | 4.21 (0.33) | 3.53 (0.67)† | 3.47 | <0.001 | | PAC, ng/dL, mean (SD) | 24.3 (11.1) | 48.9 (39.5)† | 57.0 | <0.001 | | PRA, ng/mL/h, mean (SD) | 7.5 (8.8) | 0.7 (0.9)† | 0.8 (1.6) | <0.001 | | PAC*, mean (SD) | 1.34 (0.18) | 1.59 (0.26)† | 1.67 | <0.001 | | PRA*, mean (SD) | 0.53 (0.6) | −0.52 (0.7)† | −0.63 | <0.001 | | 24-hour urinary aldosterone level, mean (SD) | 6.5 (2.4) | 6.1 (1.4) | 23.7 | <0.001 | | 24-hour urinary aldosterone level*, mean (SD) | 0.79 (0.14) | 0.77 (0.11) | 1.31 | <0.001 | | Number of hypertension medication, mean (SD) | 1.7 (0.9) | 2.0 (1.0) | 1.8 (1.0) | 0.8 | | Hypertension medication: | | | | | | CCB, (%) | 17 (55) | 30 (57) | 29 (55) | 0.598 | | ACEI or ARB, (%) | 19 (62) | 13 (25)† | 15 | 0.004 | | Thiazide, (%) | 3 (10) | 2 (3.7) | 5 (9.4) | 0.547 | | -blocker, (%) | 3 (10) | 14 (26.4)† | 22 | 0.006 | | -blocker, (%) | 9 (29) | 28 (52.8)† | 19 | 0.01 | | Spironolactone, (%) | 0 (0) | 23 (43)† | 25 | <0.001 | | Adenoma, (%) | | 30 (58) | 46 | <0.001 |
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