Reestablishment of Ischemia-Reperfusion Liver Injury by N-Acetylcysteine Administration prior to a Preconditioning Iron Protocol
Figure 4
Effects of N-acetylcysteine (NAC) and/or iron (Fe) short-term administration on liver reduced glutathione (GSH) content in rats subjected to ischemia-reperfusion (IR). Animals were treated as shown in Figure 1. Data are expressed as means ± SEM for 4 to 9 animals per group. Significance studies (; one-way ANOVA and Newman-Keuls’ test) are indicated by the letters identifying each experimental group. Inset: net changes in liver GSH levels induced by IR correspond to the differences between groups (b-a) (controls), (d-c) (Fe), (f-e) (NAC), and (h-g) (NAC + Fe).
