The Ethanol Extract of the Inner Bark of Caesalpinia pyramidalis (Tul.) Reduces Urinary Bladder Damage during Cyclophosphamide-Induced Cystitis in Rats

Table 2

Effect of ethanol extract of Caesalpinia pyramidalis (EECp) on the histopathological parameters during cyclophosphamide (CP)-induced cystitis in rats.

Group	Edema	Hemorrhage	Erosion and ulceration	Leukocyte	Total score
Saline + Vehicle	0 (0-0)	0 (0-0)	0 (0-0)	0 (0-0)	0 (0-0)
CP + Vehicle	2 (1–3)^#	2 (1–3)^#	3 (2-3)^#	3 (3-3)^#	11 (9–12)^#
CP + Mesna	0 (0-1)*	0 (0-1)*	1 (1-2)*	0 (0-0)*	2 (2–4)*
CP + EECp (100 mg/kg)	1 (0–2)	1 (0–2)	2 (2-3)	1 (1-2)*	6 (4–8)*
CP + EECp (400 mg/kg)	1 (0–2)	1 (0–2)	2 (1–3)	3 (1–3)	9 (3–11)

Data are shown as median (min–max) for 𝑛=5 animals. ^#𝑃<0.05 versus respective saline + vehicle group and *𝑃<0.05 versus respective CP + vehicle group.