Research Article

18F-Fluorothymidine-Pet Imaging of Glioblastoma Multiforme: Effects of Radiation Therapy on Radiotracer Uptake and Molecular Biomarker Patterns

Figure 1

The normal brain shows intense uptake of FDG but not FLT. (a) Comparison of intracranial % injected dose (%ID) of 18F-Fluorodeoxyglucose (18F-FDG) and 18F-Fluorothymidine (18F-FLT) radiotracers in healthy nude/athymic mice. 18F-FDG uptake is greater than 18F-FLT in intact mouse brain. (b) Visual comparison of 18F-FDG-PET and 18F-FLT-PET imaging in nude/athymic mice for comparison of intracranial radiotracer uptake (yellow arrows).
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