Evaluation of Skin Permeation and Analgesic Activity Effects of Carbopol Lornoxicam Topical Gels Containing Penetration Enhancer

Table 4

Analgesic activity of LOR formulations at a dose of 0.04 mg compared to injectable LOR dosage form (Xefo) on mice.

Time	Formulations
	LORF3	RTD	LORF8	RTD	Xefo	RTD
Initial	6.3±1.3	0	6.9±0.5	0	6.7±0.7	0
30	8.0±1.5	1.7	8.7±1.3	2.2	8.5±1.1	1.8
60	8.4±1.1	2.1	8.4±0.7	2.7	9.0±1.1	2.2
120	10.1±2	3.8	10.2±2.7	4.3	8.4±0.8	1.7
180	8.7±0.8	2.3	10.3±1.2	4	8.6±0.9	1.5