Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells

Figure 17

Histological sections in acute toxicity test (H&E staining, 20x). Histological sections of liver (first row) and kidney (second row). Untreated mices (control group) received 5 mL/kg vehicle (5% Tween 20) ((a) and (d)). Animals treated with 250 mg/kg are ((b) and (e)) and ((c) and (f)) for compounds 1 and 2, respectively. There are no significant differences in structures of liver and kidney between treated and control group.

(a)

(b)

(c)

(d)

(e)

(f)