Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells

Table 3

Effects of 250 mg/kg of 1 and 2 on liver function test.

Groups	Total protein; (g/L)	Albumin; (g/L)	Globulin; (g/L)	AP; (IU/L)	ALT; (IU/L)	AST; (IU/L)	GGT; (IU/L)
Vehicle	62 ± 1.5	12.4 ± 0.65	51.4 ± 1.1	85.3 ± 3.2	58.3 ± 3.5	251 ± 8.4	3.5 ± 0.1
1 (250 mg/kg)	65 ± 1.3	12.9 ± 0.59	53.1 ± 1.8	91.4 ± 3.4	67.7 ± 4.6	245 ± 7.5	3.3 ± 0.07
2 (250 mg/kg)	60 ± 1.0	11.8 ± 0.33	55.6 ± 1.2	87.2 ± 2.7	56.1 ± 4.2	264 ± 8.3	3.7 ± 0.09

Values are expressed as the means ± S.E.M. There are no statistically significant differences between the measurements of different groups. Significance was set at .