Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells

Table 4

Effects of 250 mg/kg of 1 and 2 on renal function test.

Groups	Sodium; (mmo/L)	Potassium; (mmol/L)	Chloride; (mmol/L)	CO2; (mmol/L)	Anion gap; (mmol/L)	Urea; (mmol/L)
Vehicle	145.6 ± 0.91	8.7 ± 0.15	109.4 ± 0.32	20.5 ± 0.34	27.0 ± 0.6	6.5 ± 0.7
1 (250 mg/kg)	151.5 ± 0.58	9.5 ± 0.18	110.8 ± 0.27	22.8 ± 0.68	26.6 ± 0.9	8.4 ± 0.5
2 (250 mg/kg)	153.3 ± 0.76	9.4 ± 0.2	114.3 ± 0.33	19.2 ± 0.21	22.7 ± 0.5	7.7 ± 0.8

Values are expressed as the means ± S.E.M. There are no statistically significant differences between the measurements of different groups. Significance was set at < 0.05.