Chronic Administration of 5-HT1A Receptor Agonist Relieves Depression and Depression-Induced Hypoalgesia

Figure 3

Effects of acute administration of 8-OH-DPAT. Acute 8-OH-DPAT treatment significantly increased locomotor activity (𝑛=8--12) (a) and pain thresholds (𝑛=8--12) (b) in the sham-operated rats but have no effect on the OB rats. Data are presented as mean±SEM.*𝑃<0.05, **𝑃<0.01.

(a)

(b)