Median Preoptic Nucleus Mediates the Cardiovascular Recovery Induced by Hypertonic Saline in Hemorrhagic Shock

Figure 3

Effects of pharmacological blockade of the MnPO on changes in mean arterial pressure (MAP; (a)), heart rate (HR; (b)), variations of renal blood flow (RBF, % baseline; (c)), renal vascular conductance (RVC % baseline; (d)), aortic blood flow (ABF, % baseline; (e)), and aortic vascular conductance (AVC, % baseline; (f)) induced by sodium overload in the rats submitted to hemorrhage. Control group received nanoinjections of 150 mM NaCl () and experimental group received nanoinjections of 4 mM Muscimol () groups. Values were expressed as means ± S.E.M. Different from time 0; ^†different from control group with . Shaded area indicates the period of hemorrhage. Dashed line represents the moment of nanoinjection into the MnPO (muscimol or vehicle) and black block indicates intravenous hypertonic saline infusion.

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