Analgesic, Anti-Inflammatory, and GC-MS Studies on Castanospermum australe A. Cunn. & C. Fraser ex Hook.

Table 2

Analgesic activities of ethanol extracts of C.  australe using hot plate method.

Groups	Dose (mg/kg)	Reaction time (seconds)
		Initial	Time after drug administration (minutes)
			30	60	120	240
Control	—	1.94±0.20	2.13±0.16	2.02±0.21	1.92±0.17	2.26±0.31
Pentazocine	30	2.36±0.18	5.18±0.13^∗	6.25±0.15^∗	8.64±0.12^∗	7.98±0.09^∗
Leaf	200	1.75±0.25	3.25±0.25^∗	4.52±0.23^∗	5.75±0.25^∗	5.50±0.16^∗
	400	2.25±0.25	3.95±0.17^∗	5.75±0.16^∗	6.59±0.21^∗	5.85±0.20^∗
Bark	200	2.13±0.21	2.97±0.15	3.68±0.19^∗	4.97±0.18^∗	4.12±0.21^∗
	400	1.93±0.18	3.12±0.20^∗	4.38±0.12^∗	5.54±0.14^∗	4.89±0.19^∗
Seed	100	2.10±0.19	3.15±0.16^∗	4.11±0.20^∗	5.06±0.21^∗	4.63±0.13^∗
	200	2.24±0.13	3.86±0.21^∗	4.79±0.22^∗	5.58±0.18^∗	4.51±0.14^∗

Values are mean of observations from six mice (𝑛=6) ± SEM.
Significantly different from control at ^∗𝑃<0.001.