Analgesic, Anti-Inflammatory, and GC-MS Studies on Castanospermum australe A. Cunn. & C. Fraser ex Hook.

Table 4

Anti-inflammatory effect of ethanol extracts of C.  australe on carrageenan induced paw oedema in rats.

Groups	Dose (mg/kg)	Oedema induced by carrageenan (mm)
		0 hr	1 hr	2 hrs	3 hrs	4 hrs
Control	—	4.86±0.32	5.49±0.11	5.92±0.32	6.53±0.18	6.96±0.21
Indomethacin	10	5.08±0.17	5.21±0.15	5.26±0.12	5.44±0.10^∗∗	5.28±0.19^∗∗
Leaf	200	4.92±0.06	5.47±0.36	5.32±0.38	5.85±0.15^∗	6.30±0.16^∗
	400	5.11±0.22	5.45±0.20	5.25±0.29	5.57±0.21^∗∗	5.85±0.12^∗∗
Bark	200	4.98±0.10	5.53±0.16	5.48±0.19	5.92±0.19^∗	6.25±0.11^∗
	400	4.96±0.14	5.34±0.20	5.36±0.12	5.67±0.13^∗∗	5.96±0.18^∗∗
Seed	100	4.93±0.25	5.73±0.23	5.30±0.23	6.01±0.13	6.13±0.16^∗∗
	200	5.04±0.51	5.48±0.12	5.35±0.18	5.87±0.17^∗	5.93±0.15^∗∗

Values are mean of observations from six rats (𝑛=6) ± SEM.
Significantly different from control at ^∗𝑃<0.01 and ^∗∗𝑃<0.001.