Lung Matrix Metalloproteinase Activation following Partial Hepatic Ischemia/Reperfusion Injury in Rats
Figure 3
Representative light micrographs of the left liver lobe of sham-operated rats (a) and of the left lobe of rats submitted to ischemia/reperfusion (I/R) (b and c). Hematoxylin and eosin staining. The sham animal shows normal hepatocyte and sinusoid morphology (a). In animals submitted to I/R the lower magnification picture (b) shows decreased eosinophilia of hepatocytes, hepatocyte vacuolation, disarrangement of hepatocyte cords, and altered sinusoidal dilatation (b). An area of extensive hepatocyte necrosis and plate disintegration (black stars) is shown under higher magnification in (c), example of grade 3. P: portal vein; CL: centrolobular vein.
