Lung Matrix Metalloproteinase Activation following Partial Hepatic Ischemia/Reperfusion Injury in Rats
Figure 4
Representative light micrographs of kidney samples obtained from sham-operated rats (a, b, and c) and from rats submitted to hepatic ischemia/reperfusion (I/R) (d, e, and f). Cortex (a, b), outer medulla (c, d), and inner medulla (e; f) are illustrated. Hematoxylin and eosin staining. With respect to the normal morphology of the cortex of sham animals (a), the cortex of animals submitted to hepatic I/R (b) shows dilated interstitium and injury to a few tubules. The insets in (a) show a normal distal convolute tubule (DCT) and in (b) patchy areas of dilatation. With respect to the normal morphology of the outer medulla of sham animals (c), the outer medulla of animals submitted to hepatic I/R shows extended areas of interstitial fluid (asterisk) apparently displacing thick limbs of Henle’s loop (THL). Respect to the inner medulla of sham animals (e), the inner medulla of animals submitted to I/R (f), shows slightly dilated thin limbs of Henle’s loop (tHL) and increased cellularity in the stromal.
