The Scientific World Journal

Review Article

Effects of Matricaria Recutita (L.) in the Treatment of Oral Mucositis

Table 2

Articles included in the review, organized in chronological order of publication: authors, year, type of cancer, treatment modality, lesion classification instrument, study groups, number of patients, form of administration, and duration of the intervention.
Reference Type of cancerTreatment modalityInjury classification toolStudy groupsNumber of patientsForm of administrationDuration of the intervention
[11]Head and neck cancerQTThe WHO scaleGroup 1. Chamomile-Prophylaxis (radiotherapy)
Group 2. Chamomile Prophylaxis (chemotherapy)
Group 3. Therapeutic Chamomile		Group 1: 20
Group 2: 46
Group 3. 32
Mouthwash14 consecutive days
[12]NCQTThe WHO scaleGroup 1: Placebo
Group 2: Chamomile		Group 1: 82
Group 2: 82		Mouthwash14 consecutive days
[13]NCQTThe WHO scaleGroup: ChamomileGroup: 01Oral30 consecutive days
[14]
Head and neck cancerRTThe WHO scaleGroup 1. Chamomile gel during the radiotherapy
Group 2. Chlorhexidine digluconate
Group 3. Chamomile gel after radiotherapy		Group 1: 7
Group 2: 7
Group 3: 8		TopicNC
[8]LeukemiaTCHThe WHO scaleGroup 1. Control
Group 2. the 0.5%
Group 2 Chamomile: Chamomile to 1%
Group 3. the chamomile 2%		Group 1: 10
Group 2: 10
Group 3: 10
Group 4: 10		Mouthwash5 consecutive days
[15]Head and neck cancerRTThe WHO scaleGroup 1. Chamomile
Group 2. Honey
Group 3. Water		Group 1: 35
Group 2: 35
Group 3: 35		Mouthwash15 consecutive days
[16]LeukemiaTCTThe toxicity scale INCGroup 1. Placebo
Group 2. Mint and Chamomile		Group 1. 33
Group 2. 27		MouthwashNC
[17]Gastric cancerQTThe WHO scaleGroup 1. Cryotherapy-Control
Group 2. Cryotherapy with chamomile		Group 1. 18
Group 2. 20		Topic22 consecutive days
[18]Non-Hodgkin lymphomaRTVisual analogue scale sterile caliperGroup 1. Placebo
Group 2. Triamcinolone Acetonide
Group 3. Chamomile		Group 1: 15
Group 2: 14
Group 3: 14		Oral10 consecutive days
[19]Acute lymphoblastic leukemiaQTThe WHO scaleSingle group: ChamomileSingle group: 31Mouthwash14 consecutive days
[20]Acute lymphoblastic leukemiaQTThe WHO scaleGroup 1: (Allopurinol, sucralfate, sodium bicarbonate, and semi-saline serum)
Group 2: Chamomile		Group 1: 31
Group 2: 31		Mouthwash14 consecutive days
UI: uninformed; ↓: reduction; ↑: increase; TNF: tumor necrosis factor; IL: interleukin; HCT: hematopoietic cell transplantation; QT: chemotherapy; RT: radiotherapy; WHO: World Health Organization.