Research Article

Z-Guggulsterone Induces Apoptosis in Gastric Cancer Cells through the Intrinsic Mitochondria-Dependent Pathway

Figure 3

Z-guggulsterone affects the caspase-3 activity and the Bax and Bcl-2 expression in SGC-7901 cells. Cells were incubated with 0, 50, and 75 µM z-guggulsterone for 24 h. (a) Caspase-3 activity level was assessed by ELISA. Data are expressed as means ± SD. vs. untreated cells. (b) Protein expression of Bcl-2 and Bax was evaluated by western blotting. Quantification of protein bands are shown in the bottom panels. β-Actin was used as a control. Data are expressed as means ± SD. vs. untreated cells. Z-gug, z-guggulsterone.
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